{"id":375,"date":"2012-04-16T14:20:07","date_gmt":"2012-04-16T05:20:07","guid":{"rendered":"http:\/\/jbtrc.com\/1_wp\/?p=375"},"modified":"2019-01-30T14:20:33","modified_gmt":"2019-01-30T05:20:33","slug":"crinet%e3%81%af%e6%96%b0%e8%a6%8f%e3%81%ae%e8%85%ab%e7%98%8d%e5%9e%8b%e3%81%8b","status":"publish","type":"post","link":"http:\/\/www.jbtrc.com\/?p=375","title":{"rendered":"CRINET\u306f\u65b0\u898f\u306e\u816b\u760d\u578b\u304b"},"content":{"rendered":"<p class=\"str\">\u3000AT\/RT\u306fINI-1\u86cb\u767d\u306e\u9670\u6027\u5316\u3092\u7279\u5fb4\u3068\u3059\u308b\u3001\u304d\u308f\u3081\u3066\u4e88\u5f8c\u4e0d\u826f\u306e\u80ce\u5150\u6027\u8133\u816b\u760d\u3067\u3042\u308b\u304c\u3001\u6700\u8fd1\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b cribriform neuroepithelial tumor (CRINET) \u306fINI-1\u9670\u6027\u3067\u3042\u308b\u304c\u4e88\u5f8c\u304c\u6bd4\u8f03\u7684\u826f\u597d\u306a\u8133\u816b\u760d\u3067\u3042\u308b\u3002<\/p>\n<p class=\"str\">\u3000Hasselblatt M, et al: Cribriform neuroepithelial tumor (CRINET): a nonrhabdoid ventricular tumor with INI1 loss and relatively favorable prognosis.J Neuropathol Exp Neurol. 2009 Dec;68(12):1249-55. [PMID:19915490]<\/p>\n<p class=\"str\">\u3000\u8457\u8005\u306f2\u4f8b\u306e\u7279\u7570\u306a\u5f62\u614b\u306e\u5c0f\u5150\u8133\u816b\u760d\u3092\u5831\u544a\u3057\u305f\u3002\u5c0f\u5150\u306b\u767a\u751f\u3059\u308b\u8133\u5ba4\u5185\u816b\u760d\u3067\u3042\u308a\u3001\u816b\u760d\u7d30\u80de\u304c\u7279\u6709\u306a\u67f5\u72b6\u3001\u7d22\u72b6\u3001\u7be9\u72b6\u306e\u4e0a\u76ae\u69d8\u914d\u5217\u3092\u793a\u3059\u3002\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u7684\u306b\u306fEMA\u304c\u7d30\u80de\u8868\u9762\u306b\u967d\u6027\u3067\u3001INI-1\u67d3\u8272\u304c\u9670\u6027\u3067\u3042\u308b\u3002\u30e9\u30d6\u30c9\u30a4\u30c9\u7d30\u80de\u306f\u8a8d\u3081\u3089\u308c\u306a\u3044\u3002SMARCB1\u907a\u4f1d\u5b50\u306e\u30a8\u30af\u30bd\u30f3\uff14\u306bhomozygous 4-bp duplication\u304c\uff11\u4f8b\u3067\u78ba\u8a8d\u3055\u308c\u305f\u3002\u8853\u5f8c\u3001\u518d\u767a\u306a\u304f\uff15\u5e74\u4ee5\u4e0a\u751f\u5b58\u3057\u3066\u304a\u308a\u3001\u4e88\u5f8c\u306f\u826f\u597d\u3067\u3042\u308b\u3002<\/p>\n<h4>JBTRC\u30b3\u30e1\u30f3\u30c8<\/h4>\n<p class=\"str\">\u3000INI-1\u67d3\u8272\u9670\u6027\u306e\u80ce\u5150\u6027\u8133\u816b\u760d\u306f\u4e00\u822c\u7684\u306bAT\/RT\u3068\u8a3a\u65ad\u3055\u308c\u3001\u6975\u3081\u3066\u4e88\u5f8c\u4e0d\u826f\u3068\u307f\u306a\u3055\u308c\u308b\u3002\u3068\u3053\u308d\u304c\u672c\u816b\u760d\u3067\u306fINI-1\u9670\u6027\u3067\u3042\u308a\u306a\u304c\u3089\u3001\u7d44\u7e54\u50cf\u306fAT\/RT\u3068\u306f\u7570\u306a\u308a\u3001\u3057\u304b\u3082\u4e88\u5f8c\u304c\u6bd4\u8f03\u7684\u826f\u597d\u3067\u3042\u308b\u306e\u3067\u3001\u6b63\u3057\u3044\u75c5\u7406\u8a3a\u65ad\u304c\u60a3\u8005\u306e\u6cbb\u7642\u3092\u9032\u3081\u308b\u4e0a\u3067\u6975\u3081\u3066\u91cd\u8981\u3067\u3042\u308b\u3002\u6700\u8fd1\u306e\u5831\u544a\u3067\u306f\u3001\u3053\u308c\u307e\u3067\u306b\uff14\u4f8b\u306e\u5831\u544a\u304c\u3042\u308a\u3001\u8853\u5f8c\u65e9\u671f\u306e\u6b7b\u4ea1\u4f8b\u3082\u3042\u308b\uff08Park et al.: 12 JAN 2012, DOI: 10.1111\/j.1440-1789.2011.01293.x [PMID: 22239490]\uff09\u3002\u3055\u3089\u306a\u308b\u75c7\u4f8b\u306e\u7a4d\u307f\u91cd\u306d\u304c\u671f\u5f85\u3055\u308c\u308b\u3002\uff08\u6587\u8cac\uff1a\u4e2d\u91cc \u6d0b\u4e00\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3000AT\/RT\u306fINI-1\u86cb\u767d\u306e\u9670\u6027\u5316\u3092\u7279\u5fb4\u3068\u3059\u308b\u3001\u304d\u308f\u3081\u3066\u4e88\u5f8c\u4e0d\u826f\u306e\u80ce\u5150\u6027\u8133\u816b\u760d\u3067\u3042\u308b\u304c\u3001\u6700\u8fd1\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b cribriform neuroepithelial tumor (CRINET) \u306fINI-1\u9670\u6027\u3067\u3042\u308b\u304c\u4e88 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-375","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"_links":{"self":[{"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=\/wp\/v2\/posts\/375","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=375"}],"version-history":[{"count":1,"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=\/wp\/v2\/posts\/375\/revisions"}],"predecessor-version":[{"id":376,"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=\/wp\/v2\/posts\/375\/revisions\/376"}],"wp:attachment":[{"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=375"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=375"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.jbtrc.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=375"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}